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. 2008 Aug;19(8):1592–1598. doi: 10.1681/ASN.2007040449

Table 6.

Predictors and risk of under- or overestimation of iCa by albumin-corrected tCa, formula 2: Univariate and multivariate logistic regression analysisa

Parameter Underestimation
Overestimation
Univariate Analysis (OR [95% CI]) Multivariate Analysis (OR [95% CI]) Univariate Analysis (OR [95% CI]) Multivariate Analysis (OR [95% CI])
Age (by 10 yr) 0.91 (0.77 to 1.08) 0.91 (0.70 to 1.18) 1.23 (1.04 to 1.45) 1.05 (0.56 to 1.98)
Albumin (g/L) 1.04 (0.98 to 1.10) 1.07 (0.89 to 1.18) 0.88 (0.85 to 0.92)b 0.73 (0.61 to 0.88)b
tCO2 (mmol/L) 0.81 (0.75 to 0.89)b 0.74 (0.64 to 0.85)b 1.00 (0.94 to 1.08) 1.42 (1.01 to 2.00)
GFR (ml/min per 1.73 m2) 0.98 (0.96 to 1.00)b 1.01 (0.98 to 1.05) 0.96 (0.91 to 1.02) 0.93 (0.87 to 1.00)
a

tCa value was corrected by formula 2 only in patients with plasma albumin concentration <35 g/L; in patients with plasma albumin concentration ≥35 g/L, the measured, noncorrected value was used in the analysis.

b

P < 0.05.