Table 2.

Comparison of clinical, biological, and histologic data between patients with or without moderate to severe graft fibrosis (IF/TA) at 12 mo and between progressors and nonprogressors^a

Parameter	Graft Fibrosis at 12 Mo			Progression of Graft Fibrosis
	IF/TA <2(n = 67)	IF/TA ≥2(n = 16)	Pb	Nonprogressors(n = 50)	Progressors(n = 33)	P
Donor age	42.60 ± 1.90	55.90 ± 3.20	0.0003	43.50 ± 2.20	47.90 ± 2.80	0.2200
Donor serum creatinine at kidney retrieval	101.40 ± 10.00	91.90 ± 7.00	0.6900	98.00 ± 10.00	100.00 ± 13.00	0.8800
Cold ischemia time (min)	1028 ± 80	1244 ± 138	0.1700	987 ± 96	1198 ± 98	0.1400
3 Mo
GFR	56.90 ± 2.00	48.70 ± 5.00	0.1100	56.80 ± 2.70	53.30 ± 3.00	0.4000
proteinuria (mg/mmol urinary creatinine)	0.04 ± 0.01	0.10 ± 0.05	0.1800	0.04 ± 0.01	0.07 ± 0.03	0.2800
Banff score at 3 mo
interstitial inflammation score	0.30 ± 0.08	0.56 ± 0.27	0.5500	0.34 ± 0.10	0.36 ± 0.15	0.8900
tubulitis score	0.46 ± 0.11	0.69 ± 0.30	0.5400	0.52 ± 0.14	0.49 ± 0.16	0.8700
chronic interstitial fibrosis score	0.25 ± 0.05	0.56 ± 0.13	0.0200	0.30 ± 0.07	0.33 ± 0.08	0.7500
tubular atrophy score	0.31 ± 0.06	0.69 ± 0.12	0.0060	0.32 ± 0.07	0.48 ± 0.09	0.1300
EPC
vimentin	0.93 ± 0.08	1.81 ± 0.28	0.0010	0.80 ± 0.09	1.55 ± 0.17	<0.0001
β-catenin	0.84 ± 0.09	1.69 ± 0.31	0.0040	0.74 ± 0.10	1.38 ± 0.18	0.0010
12 Mo
GFR	62.90 ± 2.40	47.40 ± 4.90	0.0100	61.70 ± 2.70	56.90 ± 3.90	0.3000
proteinuria (mg/mmol urinary creatinine)	0.03 ± 0.01	0.14 ± 0.10	0.3700	0.03 ± 0.06	0.09 ± 0.05	0.2200
Banff score at 12 mo
interstitial inflammation score	0.21 ± 0.07	0.94 ± 0.30	0.0010	0.22 ± 0.09	0.55 ± 0.17	0.0600
tubulitis score	0.31 ± 0.08	0.81 ± 0.25	0.0200	0.26 ± 0.09	0.64 ± 0.15	0.0200

^aBanff scores range from 0 to 3, with higher scores indicating more severe abnormalities.

^bP values are based from the Mann Whitney rank test.