Figure 5.

(A) The percentage of the outer medulla containing blocked tubules filled with protein (percentage of cast region) was determined from Gomori trichrome–stained kidney sections. The uncontrolled right kidney tended to be higher than the servocontrolled left kidney (P = 0.052). (B) Positive immunostaining of OPN was quantified in both cortex and outer medulla. OPN expression was significantly increased in the cortex of uncontrolled high-pressure right kidney compared with the servocontrolled left kidney (n = 6; *P < 0.05). No sham data were obtained for this measurement.