Table 3.

Adjusted HR, comparing calcitriol users with matched control patients^a

Parameter	Mortality		Mortality or Long-Term Dialysis
	Adjusted HR (95% CI)	P	Adjusted HR (95% CI)	P
Model 1	0.76 (0.60 to 0.95)	0.014	0.86 (0.71 to 1.04)	0.120
Model 2	0.67 (0.53 to 0.85)	<0.001	0.73 (0.60 to 0.90)	0.003
Model 3	0.74 (0.58 to 0.95)	0.016	0.80 (0.65 to 0.99)	0.038
As-treated model 3b	0.76 (0.58 to 0.99)	0.044	0.80 (0.64 to 1.01)	0.060

Model 1 adjusted for age, gender, and race and stratified by VA site. Model 2 adds baseline PTH level, eGFR, diabetes, coronary heart disease, and the Charlson comorbidity index. Model 3 adds use of an ACEI, ARB, statin, erythropoietin, or oral calcium; body mass index; systolic BP; serum levels of albumin, calcium, and phosphate; and number of nephrology visits in the previous year. HR, hazard ratio.

^bAs-treated model censors control patients at first oral calcitriol prescription.