Table 1.

Summary of average diffusion coefficients and ranges for aquaporins in COS-7 cells

	D1–3 (cm2/s)	Range at 1 s (μm)	Range at 1 min (μm)
AQP4-M1	(5.2 ± 2.2) × 10−10	0.34 ± 0.09	1.7 ± 0.4
+latrunculin	(7.2 ± 2.9) × 10−10	0.40 ± 0.10	—
+jasplakinolide	(5.6 ± 2.0) × 10−10	0.34 ± 0.07	—
M1Δ6	(7.1 ± 1.9) × 10−10	0.44 ± 0.09*	—
AQP4-M23	(5.9 ± 3.1) × 10−11	0.040 ± 0.014	0.13 ± 0.03
+latrunculin	(5.5 ± 2.8) × 10−11	0.049 ± 0.024	0.11 ± 0.07
+jasplakinolide	(4.3 ± 1.6) × 10−11	0.031 ± 0.006*	0.10 ± 0.03
M23Δ6	(6.9 ± 3.6) × 10−11	0.046 ± 0.012	0.24 ± 0.05*
AQP1	(8.1 ± 3.2) × 10−10	0.46 ± 0.14	2.0 ± 0.4

Mean ± SD D_1–3 (Equation 1) and range at 1 s (Equation 2) determined by SPT at 91 Hz. Range at 1 min determined by time-lapse SPT at 1 Hz.

*p < 0.01 when compared to untreated AQP4.