Table 5.
Regional differences in mRNA expression of CRS and cryptdins in small intestine of different mouse strains
| C57BL/6 | FVB | |
| CRS1C | D = 1.8 × 106 | D = 7.6 × 105 |
| J = 2.6 × 106 | J = 4.3 × 105 | |
| I = 2.5 × 106 | I = 1.1 × 105 | |
| CRS4C | Not present | D = 1.2 × 105 |
| J = 1.2 × 107 | ||
| I = 2.5 × 107 | ||
| Crypt1 | D = 2.2 × 106 | D = 3.3 × 106 |
| J = 3.0 × 106 | J = 3.2 × 106 | |
| I = 5.6 × 106 | I = 2.2 × 106 | |
| Crypt4 | Not present | D = 1.6 × 104 |
| J = 1.1 × 105 | ||
| I = 2.5 × 105 | ||
| Crypt4 C57BL/6 | D = 1.4 × 105 | Not present |
| J = 4.7 × 106 | ||
| I = 8.7 × 106 |
Expression of CRS and cryptdin in different parts of the small intestine measured by qRT-PCR. Tissues pooled from three mice. D = duodenum, J = jejunum, I = ileum. Numbers denotes mRNA copy numbers per 10 ng RNA. Note that C57BL/6 mice lack CRS4C-1 to 3 and cryptdin 4 and display a unique cryptdin 4 variant.