Average connectivity per functional category, using different reference sets and annotation sources. a) All b) Motile c) Proteobacteria d) Aerobic. COG functional categories and subcategories are: Poorly characterized [Not classified (-)]; Information storage and processing [Translation, ribosomal structure and biogenesis (J); Transcription (K); DNA replication, recombination and repair(L)]; Cellular processes [Cell division and chromosome partitioning (D); Posttranslational modification, protein turnover, chaperones (O); Cell envelope biogenesis, outer membrane (M); Cell motility and secretion (N); Inorganic ion transport and metabolism(P); Signal transduction mechanism (T); Intracellular trafficking, secretion, and vesicular transport (U); Defense mechanisms (V)]; Metabolism [Energy production and conversion (C); Carbohydrate transport and metabolism (G); Amino acid transport and metabolism (E); Nucleotide transport and metabolism (F); Coenzyme metabolism (I); Lipid metabolism (H); Secondary metabolites biosynthesis, transport and catabolism (Q)].