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. Author manuscript; available in PMC: 2009 Jun 2.
Published in final edited form as: Vaccine. 2008 Apr 8;26(23):2860–2872. doi: 10.1016/j.vaccine.2008.03.044

Fig. 5. Cytokines secreted from splenocytes from VACV(WR) vaccinated mice.

Fig. 5

Fig. 5

Fig. 5

Fig. 5

Fig. 5

Groups of 4 female BALB/c mice were either mock infected or were infected by scarification with 1×106 pfu VACV E3L mutants or with wtVACV as indicated. Splenocytes were harvested 8 days post-infection and exposed to wtVACV infected A20 antigen presenting cells for 36 hours. The cytokines (A) IFN-γ, (B) IL-2, (C) TNF-α, (D) IL-4, and (E) IL-5 were measured in the cell culture supernatants. Symbols represent individual mice used in each experiment. Bars indicate the average value for each group of mice. A one-way ANOVA on ranks followed by pairwise comparisons (Student-Newman-Keuls Method) was performed on all of the data.