Table 5.
Esophageal pH monitoring
| Parameter | Pre-TIF (n = 82) | 6 Months Post-TIF (n = 81) | 12 Months Post-TIF (n = 71)a |
|---|---|---|---|
| Percentage of time pH < 4 | |||
| Median (range) | 10 (3–67) | 7 (1–29) | 7 (0–22) |
| Median % reduction | 31 | 33 | |
| p | <0.001 | 0.02 | |
| Normalizedb | 33 (41%) | 26 (37%) | |
| Significantly reducedc or normalized | 46 (57%) | 43 (61%) | |
| DeMeester score | |||
| Median (range) | 34 (11–222) | 24 (4–107) | 28 (1–76) |
| Median % reduction | 28 | 24 | |
| p | <0.001 | <0.001 | |
aData were missing for eight patients because of technical problems with Bravo (n = 5), contraindications due to other health problems (n = 2), or refusal (n = 1)
bDefined by pH < 4 for ≤ 5.3% of the total monitoring time [36]
cDefined by a delta of ≥ 30% compared to baseline off PPIs