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. 1998 Nov 10;95(23):13829–13834. doi: 10.1073/pnas.95.23.13829

Figure 4.

Figure 4

PH leads to hepatocyte apoptosis in iNOS-deficient mice. (A) Representative ×400 photomicrograph from TUNEL-stained liver sections from an iNOS-deficient mouse 24 hr after PH. Apoptotic cells are indicated by bright green fluorescence (FITC+). (B) Increased apoptotic activity in hepatocytes after PH in iNOS-deficient mice. A graphical representation of apoptotic activity in liver tissue sections obtained at 24, 36, and 48 hr from control and iNOS-deficient mice is shown. The percentage of hepatocytes with positive staining by TUNEL and classic features of chromatin margination and/or condensation and nuclear fragmentation are depicted on the x axis.