Table 1.
Alanine aminotransferase and bilirubin levels in sera from iNOS-deficient and control mice
Time after PH | Serum bilirubin
|
Serum ALT
|
||
---|---|---|---|---|
Control | iNOS-null | Control | iNOS-null | |
0 h | 0.2 ± 0.05 | 0.25 ± 0.04 | 33 ± 8 | 30 ± 5 |
24 h | 1.2 ± 0.3 | 4.4 ± 1.1* | 987 ± 67 | 714 ± 105 |
36 h | 1.8 ± 0.6 | 4.9 ± 1.2* | 854 ± 221 | 1,752 ± 352* |
48 h | 0.9 ± 0.4 | 6.4 ± 2.1* | 360 ± 76 | 589 ± 82* |
72 h | 0.6 ± 0.3 | 18.5 ± 4.9* | 121 ± 42 | 477 ± 79* |
96 h | 0.5 ± 0.1 | 17.2 ± 6.2* | 54 ± 21 | 402 ± 63* |
Sera were obtained from iNOS-deficient and control mice at several different time points after PH (n = 4 or more mice/group per time point). ∗, P < 0.01 iNOS-deficient group vs. control group at the same time point. ALT, alanine aminotransferase.