Viability of cells was measured by MTT assay after 6 day treatment with letrozole as described in Materials and Methods. The treatment with letrozole is significantly more effective in MCF-7Ca and RLT-Ca cells compared to LTLT-Ca cells (p = 0.0003).
Figure 1B: Aromatase activity of MCF-7Ca, LTLT-Ca and RLT-Ca cells: Aromatase activity was measured by 3H2O release assay as described in Materials and Methods. RLT-Ca cells exhibit significantly higher aromatase activity compared to MCF-7Ca (*a, p<0.05) and LTLT-Ca cells (*b, p<0.001).