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. Author manuscript; available in PMC: 2009 Jun 15.
Published in final edited form as: Cancer Res. 2008 Jun 15;68(12):4518–4524. doi: 10.1158/0008-5472.CAN-07-5999

Figure 1. A: Effect of letrozole on proliferation of MCF-7Ca, LTLT-Ca and RLT-Ca cells in vitro.

Figure 1

Viability of cells was measured by MTT assay after 6 day treatment with letrozole as described in Materials and Methods. The treatment with letrozole is significantly more effective in MCF-7Ca and RLT-Ca cells compared to LTLT-Ca cells (p = 0.0003).

Figure 1B: Aromatase activity of MCF-7Ca, LTLT-Ca and RLT-Ca cells: Aromatase activity was measured by 3H2O release assay as described in Materials and Methods. RLT-Ca cells exhibit significantly higher aromatase activity compared to MCF-7Ca (*a, p<0.05) and LTLT-Ca cells (*b, p<0.001).