Figure 1.

EPO expression in EAE. EPO mRNA was measured in the spinal cord of control and C57BL/6 mice with MOG-induced chronic EAE at the indicated day after the immunization (A) or SJL mice with PLP-induced relapsing-remitting EAE at the peak of the disease, d 14–15 after immunization, and in the remission phase, on d 19–30 after immunization (B). The clinical score of the disease is indicated below each panel. Results are the mean ± standard error of mean (SEM) of values of at least 10 mice per group (A) and at least 5 mice per group (B), with individual samples tested in duplicate. *P < 0.05; ***P < 0.001 versus control, Student t test.