. Author manuscript; available in PMC: 2009 Aug 1.

Published in final edited form as: Pharmacol Biochem Behav. 2008 Mar 4;90(2):208–217. doi: 10.1016/j.pbb.2008.02.018

Table 1.

Effects of i.v. MDMA on locomotor activation in rats undergoing in vivo microdialysis

Dialysis Probe Site	Ambulation (cm)			Stereotypy (events)
Dialysis Probe Site	Baseline (0 min)	1 mg/kg (+20 min)	3 mg/kg (+80 min)	Baseline (0 min)	1 mg/kg (+20 min)	3 mg/kg (+80 min)
Nucleus Accumbens	87±40	838±162^*	1343±249^*	89±21	421±57^*	790±82^*
Caudate Nucleus	157±50	749±98^*	1429±277^*	174±47	431±37^*	896±63^*
Prefrontal Cortex	116±56	624±196^*	1893±338^*	123±34	353±42^*	799±66^*

Rats received 1 mg/kg MDMA at time zero, followed by 3 mg/kg 60 min later. Values are mean±SEM for N=5–6 rats/group expressed as peak effects obtained in the first sampling period after drug administration

P<0.05 compared to baseline control value for each brain region.