Table 1. Number and distribution of reported DENV protein sequences.
DENV proteinb | No. of sequencesa | ||||||||||
DENV-1 | DENV-2 | DENV-3 | DENV-4 | Total | |||||||
2005 | 2007 | 2005 | 2007 | 2005 | 2007 | 2005 | 2007 | 2005 | 2007 | Increase | |
C | 194 | 298 | 266 | 311 | 414 | 547 | 117 | 122 | 991 | 1278 | 287 |
prM | 206 | 311 | 353 | 404 | 458 | 590 | 207 | 225 | 1224 | 1530 | 306 |
E | 852 | 1051 | 1277 | 1518 | 716 | 910 | 338 | 366 | 3183 | 3845 | 662 |
NS1 | 410 | 565 | 640 | 752 | 201 | 308 | 142 | 159 | 1393 | 1784 | 391 |
NS2a | 150 | 238 | 132 | 173 | 90 | 169 | 121 | 125 | 493 | 705 | 212 |
NS2b | 136 | 224 | 130 | 163 | 104 | 183 | 40 | 44 | 410 | 614 | 204 |
NS3 | 98 | 186 | 145 | 178 | 216 | 297 | 30 | 34 | 489 | 695 | 206 |
NS4a | 91 | 178 | 128 | 162 | 70 | 151 | 28 | 32 | 317 | 523 | 206 |
NS4b | 89 | 176 | 129 | 163 | 70 | 150 | 109 | 113 | 397 | 602 | 205 |
NS5 | 92 | 179 | 151 | 187 | 181 | 267 | 191 | 195 | 615 | 828 | 213 |
Total | 2318 | 3406 | 3351 | 4011 | 2520 | 3572 | 1323 | 1415 | 9512 | 12404 | 2892 |
Collected from the NCBI Entrez protein database
Manually processed after multiple sequence alignments and use of the known DENV cleavage sites