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. 2008 Aug 13;2(8):e272. doi: 10.1371/journal.pntd.0000272

Table 1. Number and distribution of reported DENV protein sequences.

DENV proteinb No. of sequencesa
DENV-1 DENV-2 DENV-3 DENV-4 Total
2005 2007 2005 2007 2005 2007 2005 2007 2005 2007 Increase
C 194 298 266 311 414 547 117 122 991 1278 287
prM 206 311 353 404 458 590 207 225 1224 1530 306
E 852 1051 1277 1518 716 910 338 366 3183 3845 662
NS1 410 565 640 752 201 308 142 159 1393 1784 391
NS2a 150 238 132 173 90 169 121 125 493 705 212
NS2b 136 224 130 163 104 183 40 44 410 614 204
NS3 98 186 145 178 216 297 30 34 489 695 206
NS4a 91 178 128 162 70 151 28 32 317 523 206
NS4b 89 176 129 163 70 150 109 113 397 602 205
NS5 92 179 151 187 181 267 191 195 615 828 213
Total 2318 3406 3351 4011 2520 3572 1323 1415 9512 12404 2892
a

Collected from the NCBI Entrez protein database

b

Manually processed after multiple sequence alignments and use of the known DENV cleavage sites