Table 4.
Adjusted odds ratio for death and/or default outcomes among HIV-infected TB patients.
1. Those with cure, complete, death outcomes | ||||||||
Comparison groups versus non-reactive | All patients | Culture-confirmed TB | ||||||
n | AOR | 95% CI | n | AOR | 95% CI | |||
L | U | L | U | |||||
HBsAg + | 385 | 1.0 | 0.3 | 3.3 | 188 | 0.5 | 0.1 | 4.9 |
Anti-HCV + | 504 | 1.1 | 0.6 | 1.9 | 253 | 1.4 | 0.6 | 3.6 |
HBsAg and anti-HCV + | 374 | 2.1 | 0.6 | 7.6 | 185 | 4.8 | 0.5 | 42.9 |
2. Those with cure, complete, death, and default outcomes | ||||||||
Comparison groups versus non-reactive | All patients | Culture-confirmed TB | ||||||
n | AOR | 95% CI | n | AOR | 95% CI | |||
L | U | L | U | |||||
HBsAg + | 420 | 2.7 | 1.1 | 6.4 | 207 | 5.5 | 1.4 | 21.9 |
Anti-HCV + | 549 | 1.2 | 0.8 | 2.0 | 281 | 2.0 | 1.0 | 4.0 |
HBsAg and anti-HCV + | 401 | 1.4 | 0.4 | 4.7 | 198 | 1.7 | 0.3 | 11.2 |
+ sign indicates reactive; bold type indicates statistical significance (p < 0.05); TB, tuberculosis, HIV, human immunodeficiency virus; AOR, adjusted odds ratio; CI, confidence interval; L, lower bound; U, upper bound; HBsAg, hepatitis B surface antigen; HCV, hepatitis C virus, N, number of patients included in the model.
*Adjusted odds ratios from multivariate logistic regression analyses adjusted for TB disease severity, HIV disease severity, co-trimoxazole use, fluconazole use, anti-retroviral use, whether or not received directly observed therapy, hospitalized at enrollment and been treated for TB previously