Table 2.
Checkpoint dependent and tissue specific induction of IR-induced genes.
| qRT-PCR | GeneChip | ||||||
| gene | N2 wild type | mrt-2(e2663) | cep-1 (lg12501) | N2 wild type | N2 wild type | cep-1 (lg12501) | |
| germlines | embryos | ||||||
| F49F1.6 | 39.34 | 45.38 | 49.03 | ND | 2.43 | 155.32 | 98.58 |
| dod-22 | 12.06 | 6.29 | 10.54 | ND | ND | 9.90 | 8.55 |
| lys-2 | 5.28 | 5.28 | 5.43 | 5.46 | 5.66 | 3.52 | 3.00 |
| pme-5 | 2.00 | 4.88 | 1.37 | 1.03 | 1.78 | 5.68 | 6.82 |
| Y47G7B.2 | 2.39 | 1.68 | -1.01 | 1.23 | 2.27 | 1.78 | 1.01 |
| egl-1 | 3.93 | 1.89 | -1.61 | 6.96 | -6.19 | 2.39 | -1.20 |
| ced-13 | 81.43 | 2.99 | -1.30 | -1.43 | 21.86 | 1.73 | 1.00 |
Quantitative RT-PCR was performed on samples taken 2 h after gamma-irradiation with 120 Gy. GeneChip refers to the Affymetrix GeneChip experiment using worms 2 h after X-ray treatment. Values correspond to fold changes.