Table 1.
Putative HIV receptor expression on oral keratinocytes
Receptor | Function |
TE (Mean ± SD)a |
TERT-2 (Mean ± SD)b |
CD104 (β4 integrin) | transmembrane protein expressed predominantly in epithelial cells [32] | 80 ± 11 | 83 ± 4 |
HSPGs | HIV gp120 binding [70] | 13 ± 7 | 91 ± 20 |
GalCer | HIV gp120 binding [71] | 4 ± 0.1 | < 1 |
CD4 | HIV gp120 binding [72] | < 1.0 | < 1 |
CXCR4 | X4-tropic chemokine co-receptor [73] | < 1.0 | 3.5 ± 2 |
CCR5 | R5-tropic chemokine co-receptor [73] | < 1.0 | < 1 |
CD3, CD11a/LFA-1, CD32, CD64, CD89, DC-SIGN, Macrophage Mannose Receptor | < 1.0 | Not tested | |
Human fibroblast | 4 ± 4 | Not tested |
a Mean ± SD of four independent experiments (1 experiment from tissue no. 164 and 193, and 2 experiments from tissue no. 196)
b Mean ± SD of three independent experiments