Table 1.
TGF-β inhibition upregulates mRNA (as measured by real-time RT-PCR for some pro-inflammatory cytokines, chemokines and chemo-attractants)
| Primer | Fold change | p-value |
|---|---|---|
| IP-10 (CXCL10) | 2.0 | 0.001 |
| MIG (CXCL9) | 2.5 | 0.01 |
| Rantes (CCL5) | 1.0 | NS |
| TNF-α | 6.4 | <0.001 |
| iNOS | 1.4 | 0.03 |
| IL-12 | 2.7 | 0.001 |
| Arginase | 0.4 | <0.001 |
| TGF-β | 1.0 | NS |