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Animals were vaccinated with either wild type E7 (◯,▵,□) or empty vector (•,▴,▪) and were then challenged with each of the CRPV genomes including wild type. Vaccination resulted in a reduction in size of all papillomas. Volumes of wild type, E7/8, E7/14 and E7/18 papillomas were reduced 30–50%, and volumes of E7/22 papillomas were reduced 75% (see Table 1). Figure shows results for wild type (◯,•), E7/18 (▵,▴) and E7/22 (□,▪) papillomas.
