Figure 5. SCH-N does not alter the level of proinflammatory cytokines.

Mice were exposed to filtered air or cigarette smoke as described, and treated with SCH-N (gray bars) or vehicle (black bars). IL-6 (A), TNF-α (B) and PGE2 (C) were measured in BAL fluid by commercially available ELISA and EIA, as described. Results shown are from a representative experiment with 6 mice per group. *=significant difference from air-exposed controls (p<0.05); the differences between smoke-exposed mice treated with vehicle or drug are not significant.