Table 2.
Dominant-negative nNOS and COX-2 constructs block NMDA neurotoxicity
| Constructs | No. of dead cells with NMDA treatment/no. of dead cells without NMDA treatment, -fold |
|---|---|
| GFP | 3.75 ± 0.35 |
| GFP-nNOS-PDZ | 1.67 ± 0.18* |
| GFP-COX-2 (484–604) | 1.56 ± 0.25 |
*Significantly higher than all other conditions (P < 0.05).