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Mice receiving prophylactic anti-MCH treatment develop attenuated TNBS colitis. Mice were treated daily with anti-MCH or control antibody (1 mg/kg) starting the day before TNBS exposure for a total of three doses. Histological scoring of colonic inflammation was performed in H&E-stained sections under a light microscope. *, p < 0.05 compared to control. (Calibration bar = 100 μm.)
