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Comparison of the PD-1/PD-L2 and the CTLA-4/B7–1 complexes. (Upper Left) IgV domains of PD-1 (green) and PD-L2 (cyan) in the PD-1/PD-L2 complex. (Upper Right) IgV domains of CTLA-4 (blue) and B7–1 (magenta) in the CTLA-4/B7–1 complex. (Lower) Overlay of the entire PD-1/PD-L2 and CTLA-4/B7–1 complexes by superimposition of PD-1 and CTLA-4.
