Fig. 2.
IA training induces the activation of ERK2 and CaMKII in the CA1 region of the dorsal hippocampus and the activation of ERK2 in the BLA. Representative immunoblots and densitometric quantification show the time course of the IA training-induced increase in αCaMKII (pCaMKII), GluR1 (pGluR1), ERK2 (pERK2), and TH (pTH) phosphorylation levels in total homogenates prepared from the BLA or the CA1 region of the dorsal hippocampus (CA1). IA-trained rats were killed immediately (0), 30 or 180 min after training. n = Naïve animals, i.e., rats that were killed without submitting them to any specific behavioral protocol. Data are expressed as mean ± SEM. ***, P < 0.001, **, P < 0.01, and *, P < 0.05 vs. naïve in Dunnett's test after ANOVA; n = 5 per group.
