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. 2008 Jul 22;105(30):10595–10600. doi: 10.1073/pnas.0803671105

Fig. 2.

Fig. 2.

Dual GSI plus Qa therapy prevented dendritic degeneration more effectively than GSI or Qa alone. (A–C) Golgi silver staining of dendrites in layer 6 of the cortex (A), the hippocampus CA1 region (B), and the medial nuclei of the thalamus (C) shows severe dendrite loss in infected DMSO mice and prevention of loss with GSI plus Qa treatment. (D–F) Measurements of dendrite loads in each of the three brain regions as a function of treatment are shown. Note the microscopic field used to measure dendrite loads in the cortex spanned cortical layers 5 and 6, whereas the micrographs in A show cortex layer 6 only. Student's t test probabilities (n = 3 mice each): *, P ≤ 0.05; **, P ≤ 0.01. Scale bars represent 30 μm and apply to each image in the same row.