Figure 1.

Neighbor-joining phylogenetic tree of eukaryotic PRA1 proteins. Proteins from Arabidopsis are in boldface, and proteins from other species are indicated by a two-letter prefix (Cr, Chlamydomonas reinhardtii; Op, Ostreococcus lucimarinus; Os, Oryza sativa; Ot, Ostreococcus tauri; Pp, Physcomitrella patens; Pt, Populus trichocarpa). Nonplant proteins are given with their original name from the OrthoMCL database (cel, Caenorhabditis elegans; cin, Ciona intestinalis; cme, Cyanodioschyzon merolae 10D; dme, Drosophila melanogaster; dre, Danio rerio; hsa, Homo sapiens; mmu, Mus musculus; ncr, Neurospora crassa OR74A; sce, Saccharomyces cerevisiae S288C; spo, Schizosaccharomyces pombe; tni, Tetraodon nigroviridis). Branches with fewer than 70% bootstrap were collapsed. The animal PRA1, PRAF2, and PRAF3 clusters are shaded in gray.