Table 2.

Absolute cell numbers of hemopoietic subpopulations in control and terminally ill HOX11 transgenic mice

	Control, n = 5	HOX11, n = 8
Bone marrow
Total cell number/femur	2.14  ±  0.3 × 107	2.63  ±  1.6 × 107
B220	1.72  ±  1.1 × 106	1.86  ±  1.4 × 106
Mac-1	1.09  ±  0.2 × 107	1.34  ±  0.6 × 107*
Thymus
Total cell number	2.66  ±  1.9 × 107	2.60  ±  1.0 × 107
B220	1.77  ±  2.1 × 106	4.44  ±  5.2 × 106
CD4−CD8−	3.83  ±  3.4 × 106	8.44  ±  5.8 × 106
CD4+CD8+	1.51  ±  1.0 × 107	1.14  ±  1.1 × 107
CD4+CD8−	4.97  ±  4.2 × 106	4.46  ±  2.8 × 106
CD4−CD8+	2.71  ±  1.8 × 106	1.74  ±  0.8 × 106
Spleen
Total cell number	3.68  ±  0.6 × 108	5.62  ±  3.0 × 108
B220	1.77  ±  0.8 × 108	1.88  ±  0.9 × 108
Mac-1	1.82  ±  0.3 × 107	8.72  ±  8.5 × 107
CD4+	5.98  ±  0.3 × 107	5.22  ±  3.0 × 107
CD8+	2.55  ±  0.4 × 107	2.43  ±  2.19 × 107
Lymph nodes
Total cell number	2.31  ±  1.1 × 106	5.01  ±  3.1 × 106
B220	6.58  ±  3.1 × 105	1.46  ±  0.8 × 106
Mac-1	6.64  ±  1.9 × 104	2.46  ±  1.2 × 105*
CD4+	1.15  ±  0.9 × 106	2.30  ±  2.3 × 106
CD8+	4.30  ±  4.1 × 106	6.72  ±  6.4 × 105
Peripheral blood
Total number leukocytes	3.03  ±  1.4 × 106	3.33  ±  0.9 × 106
B220	1.18  ±  0.8 × 106	1.19  ±  0.7 × 106
Mac-1	5.58  ±  1.9 × 105	9.17  ±  3.1 × 105
CD4+	4.33  ±  0.5 × 105	5.41  ±  4.4 × 105
CD8+	1.54  ±  0.7 × 105	2.40  ±  1.1 × 105

Results are expressed as mean ± SD. 

^*Statistical analysis using a Student’s t test showed a significant difference between control and HOX11 transgenic mice (P ≤ 0.05).