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. 2008 Apr 14;79(3):481–491. doi: 10.1093/cvr/cvn094

Table 2.

M5 compared with N6

Actin sliding speed, M5/N6 Actin–tropomyosin sliding speed, M5/N6 Actin–tropomyosin–troponin sliding speed at pCa5, M5/N6 Actin–tropomyosin–troponin sliding speed at pCa9, M5/N6 Actin–tropomyosin–troponin fraction motile at pCa9, M5/N6
Preparation 1 1.28 1.21 1.46 1.52 2.78
Preparation 2 1.44 1.18 1.43 1.32 1.01
Preparation 3 1.60 1.24 1.22 1.12 1.77

Comparison of motility parameters of non-failing heart myosin (N6) and HOCM myosin, M5. M5 has a consistently hypercontractile molecular phenotype.