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. Author manuscript; available in PMC: 2009 Jul 1.
Published in final edited form as: Int J Parasitol. 2008 Jan 26;38(8-9):901–912. doi: 10.1016/j.ijpara.2007.12.009

Fig. 3.

Fig. 3

Transmission electron microscopy image reconstruction of native mitochondrial RNA-binding protein (MRP) 1/MRP2 complexes isolated from Trypnaosoma brucei. (A) View of the MRP1/MRP2 complex prior to the RNase treatment. Clearly visible in the structure is the central hole in the cavity of the MRP1/MRP2 heterotetramer complex. (B) View of the same complexes after the RNase treatment. Comparison of the RNase-treated and non-treated complexes indicates that the RNA does not bind in the central cavity but on the surface and/or the outside of the complex. (C) Superimposition of the crystal structure on an averaged electron microscopy picture of the MRP1/MRP2 complex.