Table 1.
Consistently differentially expressed genes at all measurements after LSR knock down by both LSR siRNAs (log2 scale).
| Location | Gene | LSR1 | LSR2 | |||||
| 18 h | 48 h | 72 h | 18 h | 48 h | 72 h | |||
| Cytoplasm | AKAP12 | A kinase (PRKA) anchor protein (gravin) 12 | 1.2 | 1.8 | 1.9 | 1.1 | 2.1 | 2.1 |
| Extracell. Space | FST | follistatin | 1.8 | 3.2 | 2.8 | 1.9 | 3.9 | 3.6 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 1.3 | 1.6 | 1.1 | 1.3 | 1.6 | 1.2 | |
| IL1A | interleukin 1, alpha | 1.3 | 2.0 | 1.7 | 1.4 | 2.1 | 2.2 | |
| CYR61 | cysteine-rich, angiogenic inducer, 61 | 1.1 | 2.6 | 2.2 | 1.0 | 2.3 | 2.6 | |
| EDN1 | endothelin 1 | 1.2 | 3.1 | 1.8 | 1.2 | 2.7 | 2.6 | |
| GLIPR1 | GLI pathogenesis-related 1 (glioma) | 1.4 | 2.2 | 2.6 | 1.7 | 2.8 | 2.8 | |
| PTHLH | parathyroid hormone-like hormone | 1.5 | 3.3 | 3.8 | 1.0 | 3.0 | 3.2 | |
| Nucleus | EGR1 | early growth response 1 | 2.0 | 3.7 | 2.5 | 2.9 | 1.6 | 3.5 |
| MYOCD | myocardin | 1.1 | 1.9 | 2.1 | 1.1 | 1.5 | 1.8 | |
| Plasma Membrane | TSPAN8 | tetraspanin 8 | -1.1 | -1.9 | -2.5 | -1.9 | -3.1 | -3.0 |
| MALL | mal, T-cell differentiation protein-like | 1.7 | 1.3 | 1.1 | 1.4 | 1.5 | 1.3 | |
| NEXN | nexilin (F actin binding protein) | 1.4 | 1.5 | 1.3 | 1.4 | 1.7 | 1.4 | |
| LSR | lipolysis stimulated lipoprotein receptor | -3.6 | -2.8 | -2.4 | -2.6 | -1.6 | -1.3 | |
| Unknown | TMCO1 | transmembrane and coiled-coil domains 1 | 2.0 | 1.8 | 1.4 | 1.9 | 1.7 | 1.3 |
| TRIM31 | tripartite motif-containing 31 | -1.3 | -2.0 | -1.5 | -1.2 | -1.9 | -1.7 | |
Genes in bold are known by the Ingenuity Pathway Knowledge Base. Figures indicate log2 fold change at various time points.