Table 2.
Candidate genes relating to aspirin resistance which were analysed statistically
| Gene (no of studies) | Variant | Genetic model | Total no: aspirin resistant | Total no: aspirin sensitive | OR (95% CI) | P-value |
|---|---|---|---|---|---|---|
| GPIIIa (10) | PlA1/A2 | Dominant | 295 | 673 | 1.14 (0.84, 1.54) | 0.4 |
| GPIa (4) | C807T | Dominant | 90 | 204 | 1.37 (0.81, 2.31) | 0.24 |
| COX-1 (3) | A842G (C50T) | Dominant | 27 | 152 | 1.07 (0.41, 2.77) | 0.89 |
| P2Y12 (3) | H1/H2 | Dominant | 66 | 226 | 0.90 (0.48, 1.68) | 0.73 |
| P2Y1 (2) | A1622G | Dominant | 101 | 267 | 0.80 (0.48, 1.33) | 0.39 |