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. 2008 Aug 4;14:1414–1428.

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This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Transcriptional regulatory network diagram for transcription response element associated with human promoter regions. The graphical representation was derived using GraphViz as described in Methods. The ellipses and diamonds represent individual genes divided into upregulated (blue) and down-regulated (green) clusters. The boxes represent TREs, with arrows indicating gene-TRE associations. Corresponding network diagrams for mouse, rat and chick promoter regions are shown in Appendix 18 through Appendix 20.