Table 10. Counts, odds ratio, and p-value for testing independence for all observed diplotypes (rs10490924 x rs11200638).
| GG/GG | GG/GA | GG/TG | TG/TG | GG/TA | GA/TA | TG/TA | TA/TA | |
|---|---|---|---|---|---|---|---|---|
| Case |
134 |
1 |
0 |
0 |
11 |
33 |
5 |
0 |
| Control |
89 |
6 |
5 |
2 |
37 |
139 |
73 |
13 |
| Odds ratio |
1 |
--- |
--- |
--- |
5.06 (95% CI: 2.45,10.45) |
6.34 (95% CI: 3.99,10.09) |
21.98(95% CI: 8.54,56.55) |
--- |
| P-value | --- | 0.02 | 0.01 | 0.16 | 2.62e-6 | 1.51e-16 | 2.41e-18 | 1.16e-5 |
Odds ratios and their CIs are based on logistic regression models. Where counts are less than 6, ORs are ignored; p-values are for Fisher’s exact tests. The phase-known diplotypes and estimated diplotypes were pooled, which were sufficient for haplotype analyses. P-value for testing independence of disease and all diplotypes is 4.76e-24.