Table 3. Comparison of best cut off values for IPCS PSS, GCS, pulse, blood pressure and intubation.

	All OPs	Fenthion	Chlorpyrifos	Dimethoate
IPCS PSS cut off Grade 2 or 3
AUC Sensitivity Specificity Likelihood ratio n (% missing data)	0.81 (0.77 to 0.85) 0.78 (0.71 to 0.84) 0.79 (0.76 to 0.81) 3.7 1365 (0)	0.67 (0.52 to 0.84) 0.50 (0.25 to 0.75) 0.86 (0.78 to 0.92) 3.6 123 (0)	0.75 (0.65 to 0.83) 0.63 (0.47 to 0.77) 0.82 (0.78 to 0.85) 3.4 533 (0)	0.88 (0.84 to 0.92) 0.95 (0.99 to 0.99) 0.71 (0.65 to 0.77) 3.3 334 (0)
GCS cut off ≤ 13
AUC Sensitivity Specificity Likelihood ratio n (% missing data)	0.84 (0.80 to 0.87) 0.79 (0.72 to 0.84) 0.79 (0.77 to 0.82) 3.8 1364 (0.1)	0.69 (0.54 to 0.85) 0.43 (0.20 to 0.70) 0.87 (0.79 to 0.93) 3.3 123 (0)	0.78 (0.71 to 0.87) 0.70 (0.54 to 0.83) 0.80 (0.77 to 0.84) 3.6 533 (0)	0.91 (0.87 to 0.95) 0.94 (0.79 to 0.95) 0.71 (0.79 to 0.88) 3.3 334 (0)
Systolic BP cut off ≤ 100
AUC Sensitivity Specificity Likelihood ratio n (% missing data)	0.64 (0.59 to 0.70) 0.45 (0.37 to 0.52) 0.85 (0.84 to 0.88) 3.3 1259 (7.8)	0.41 (0.34 to 0.58) 0.19 (0.04 to 0.46) 0.84 (0.75 to 0.90) 1.2 115 (6.5)	0.52 (0.40 to 0.64) 0.24 (0.11 to 0.40) 0.88 (0.84 to 0.91) 1.9 494 (7.3)	0.81 (0.74 to 0.87) 0.69 (0.57 to 0.79) 0.82 (0.76 to 0.87) 3.8 311 (6.8)
Pulse cut off ≤ 60
AUC Sensitivity Specificity Likelihood ratio n (% missing data)	0.44 (0.40 to 0.50) 0.09 (0.05 to 0.15) 0.97 (0.53 to 0.59) 3.4 1328 (2.7)	0.40 (0.33 to 0.58) 0.0 (0.0 to 0.22) 0.96 (0.91 to 0.99) 0.0 121 (1.63)	0.49 (0.38 to 0.59) 0.18 (0.08 to 0.34) 0.98 (0.96 to 0.99) 8.7 524 (1.7)	0.45 (0.38 to 0.53) 0.09 (0.04 to 0.18) 0.98 (0.96 to 0.99) 5.7 324 (3.0)
Intubation
AUC Sensitivity Specificity Likelihood ratio n (% missing data)	0.66 (0.61 to 0.71) 0.38 (0.30 to 0.45) 0.95 (0.94 to 0.96) 7.9 1365 (0)	0.53 (0.37 to 0.69) 0.06 (0.00 to 0.30) 1.00 (0.97 to 1.00) - 123 (0)	0.60 (0.50 to 0.70) 0.23 (0.12 to 0.39) 0.97 (0.95 to 0.98) 6.7 533 (0)	0.72 (0.65 to 0.79) 0.49 (0.38 to 0.61) 0.95 (0.91 to 0.97) 9.6 334 (0)

The range in parenthesis denotes the 95% CI of the sensitivity, specificity and AUC of the ROC.