. Author manuscript; available in PMC: 2008 Aug 1.

Published in final edited form as: QJM. 2008 Mar 4;101(5):371–379. doi: 10.1093/qjmed/hcn014

Table 4. Previous scoring systems in OP poisoning.

Reference	Parameters used in grading system	Validation	n (deaths)	Ability to predict mortality
Reference	Parameters used in grading system	Validation	n (deaths)	Sensitivity (95% CI)	Specificity (95% CI)
Bardin et al, 1994⁵	Clinical findings (rhonchi, consciousness, hypotension), CXR, ABG	Retrospective	62 (3)	1.00^* (0.29 to 1.00)	0.47^* (0.34 to 0.60)
Bilgin et al, 2005¹⁹	APACHE II > 16	Retrospective	32 (7)	1.00 (0.59 to 1.00^*)	0.80 (0.59 to 0.93^*) AUC 0.92
	Simplified acute physiology score (SAPS) II >29	Retrospective	32 (7)	1.00 (0.59 to 1.00^*)	0.76 (0.55 to 0.91^*) AUC 0.89
	GCS <9	Retrospective	32 (7)	0.86 (0.42 to 1.00^*)	0.72 (0.51 to 0.88^*) AUC 0.90
Goel et al, 1998⁶	Clinical findings (GCS, Pupil size, Fasciculations, Respiratory failure)	Retrospective	103 (9)	1.00^* (0.66 to 1.0)	0.65^* (0.54 to 0.74)
Grmec et al, 2004⁷	GCS ≤ 6	Retrospective	65 (4)	0.84 (0.76 to 0.91)	0.89 (0.84 to 0.93)
Grmec et al, 2004⁷	QTc on ECG	Retrospective	65 (4)	0.90 (0.84 to 0.93)	0.83 (0.71 to 0.93)
Lee and Tai 2001 ⁸	APACHE II >26	Retrospective	23 (3)	1.00^* (0.29 to 1.00)	0.95^* 0.75 to 1.00
Sennayake et al, 1993¹⁰	Clinical findings (Miosis, Fasciculations, Respiratory rate, Bradycardia, level of consciousness)	Prospective	173 (10)	0.80^* (0.44 to 0.97)	0.86^* (0.80 to 0.91)
Sungurtekin et al 2006²⁰	APACHE II >11	Retrospective	48 (11)	0.90 (0.56 to 0.98)	0.60 (0.42 to 0.75) AUC 0.79
	SAPS II > 28	Retrospective	48 (11)	0.90 (0.56 to 0.98)	0.81 (0.65 to 0.92) AUC 0.85
	GCS < 9	Retrospective	48 (11)	0.64 (0.31 to 0.89)	0.78 (0.62 to 0.91) AUC 0.64

Values for sensitivity (95% CI), specificity (95% CI) and AUC calculated from the published data