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. 2008 Jul;21(3):466–472. doi: 10.1128/CMR.00059-07

TABLE 5.

Examples of travel itineraries, risk estimation, and suggested advice for adults and nonpregnant travelers

Country Travel itinerary Risk estimation Recommendation
Vietnam 3 wk traveling from Hanoi to Ho Chi Minh City primarily along the coast Very limited; the only area of Vietnam where the annual parasite rate exceeds 10 per 1,000 individuals per yr is in the central highlands bordering Laos No chemoprophylaxis; use impregnated bed nets and repellants; carry SBET
South Africa 3 days in Kruger National Park and 2 wk traveling in the rest of the country down to Cape Town Risk in Kruger National Park but not the remaining part of the visit; chloroquine resistance reported Chemoprophylaxis recommended in Kruger National Park, and doxycycline, mefloquine, or atovaquone-proguanil (most practical option for short-term use) can be used
Mexico Visiting Yucatan including Palenque and San Cristobal de la Casas for 2 wk Low-risk area No chemoprophylaxis; use impregnated bed nets and repellants
Tanzania Pregnant student who planned a 3-mo stay in rural Tanzania found out she was pregnant gestational wk 12 6 wk before leaving High-risk area; chemoprophylaxis highly needed; chloroquine resistance widespread Doxycycline is contraindicated in pregnancy, and data are lacking on the safety of atovaquone-proguanil; mefloquine is considered safe after gestational wk 16
Ghana 12-wk-old infant; Ghanean family living in Europe had their first child 3 mo ago and want to visit their family in Ghana living in the rural areas north of Kumasi High-risk area; recommend deferral of travel; chemoprophylaxis and mosquito bite protection essential Doxycycline contraindicated; mefloquine possible for infants weighing >5 kg; tablets can be cut and crushed; atovaquone-proguanil is recommended by some authorities for children >5 kg