Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
PNU-286607 (QPT-1) specifically inhibits DNA synthesis in a S. aureus macromolecular synthesis assay. The dose-dependent reduction of [14C]thymidine but not other radiolabeled precursors of macromolecular synthesis occurs upon treatment of growing S. aureus cells (strain UC9218) with PNU-286607. The MIC for this strain is 1 μg/ml (2.6 μM) (Table 1).
