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Visual predictive check of population pharmacokinetic model for miltefosine. The open dots present data for all analyzed study samples (n = 382) from 31 Dutch military personnel with cutaneous leishmaniasis (L. major) contracted in Afghanistan. All patients were treated with 50 mg of oral miltefosine three times daily for a total of 28 days. The gray area shows the 90% confidence interval of the model predictions; the dashed line displays the median predicted concentrations.
