Skip to main content
. 2008 Jun 9;76(8):3577–3586. doi: 10.1128/IAI.00269-08

FIG. 4.

FIG. 4.

BALF albumin concentration from rats at 3, 6, 24, 48, 72, and 168 h post-challenge with different titers of A. baumannii strain 307-0294. Rats were given 7.0 × 106, 5.8 × 107, 3.5 × 108, 4.3 × 108, and 7.7 × 109 CFU of 307-0294 by intratracheal instillation, and cell-free BALF was obtained at 3, 6, 24, 48, 72, and 168 h for determination of albumin. There was a significant decrease in the concentration of BALF albumin at 24 h in rats challenged with 7.0 × 106 and 5.8 × 107 CFU compared to rats challenged with 3.5 × 108 CFU (*, P = 0.0008 and 0.002, respectively) and at 168 h in rats challenged with 7.0 × 106 and 5.8 × 107 CFU compared to rats challenged with 3.5 × 108 CFU (*, P = 0.006 and 0.008, respectively). There was a trend for a decrease in the concentration of BALF albumin at 6 h in rats challenged with 7.0 × 106 CFU compared to rats challenged with 4.3 × 108 CFU (&, P = 0.03), at 24 h in rats challenged with 7.0 × 106 and 5.8 × 107 CFU compared to rats challenged with 7.7 × 109 CFU (&, P = 0.01 and 0.02, respectively), and at 168 h in rats challenged with 7.0 × 106 CFU compared to rats challenged with 4.3 × 108 CFU (&, P = 0.01). Data are means ± standard errors of the means for n = 3 for each challenge titer and time point.