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LD50 of B. bronchiseptica ST27 strains and RB50ΔcyaA. (A) Groups of three to four mice were inoculated intranasally with the indicated doses of strains 443 (filled) or 189 (open), which are both ST27 strains. (B) Groups of three to four C57BL/6 mice were inoculated intranasally with the indicated doses of RB50ΔcyaA. Survival curves were generated by inoculating mice and determining the percent survival over a 28-day period.
