FIG. 2.

KP9-specific TCR clonotype modulations over time. TCR clonotypes present in samples from individual animals could be divided into three categories, (i) those that were present at all of the time points studied after vaccination and challenge (relatively stable), (ii) those not present after vaccination that emerged after challenge (emerging), and (iii) those present after vaccination that were subsequently lost after challenge (declining). Examples of clonotypes from each animal that fall into each of these three categories are illustrated here, with clonotype identities indicated by the keys on the right. Other clonotypes are displayed as random shades of gray.