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Injury is increased in cd73−/− mice. CD73-deficient (CD73−/−) mice or age, weight, and gender-matched littermate controls (WT) were subjected to 15 min of ischemia, followed by 3 h of reperfusion. Injury was measured for the following parameters: Intestinal MPO (A), lung MPO (B), AST (C), ALT (D), IL-6 (E), and IL-1 (F). All results are expressed as mean ± se; 8–12 mice/group.
