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. 1998 Nov 10;95(23):13865–13868. doi: 10.1073/pnas.95.23.13865

Figure 1.

Figure 1

Inhibition of PR-mediated VLPs cleavage by Vif and Vif peptides in vitro. VLPs were purified and subjected to cleavage with HIV-1 PR, electrophoresis, and Western blot staining with anti-Gag. The lanes show VLPs incubated alone (G); VLPs incubated with PR (G + P); VLPs incubated with PR and Vif or BSA at molar ratios of 10, 2.5, and 0.6:1 PR, respectively; and VLPs incubated with PR and Vif21–65 or H2A peptides at molar ratios of 20, 10, 5, 2.5, and 1.2:1 PR, respectively. The mobilities of Gag polyprotein p55, intermediate cleavage product p41, and final product p24 are indicated.