Results demonstrating the effects on K157C charge transfer in oocytes treated with various 1 mM sulfhydryl-specific reagents (MTS derivatives) in 100 mM Na+ (n ≥ 3 for each compound tested). The error bars represent SE. A one-way analysis of variance (ANOVA) was conducted to determine whether significant differences existed in the maximal charge transfer (Qmax) of K157C (capacitive currents removed), empty pMT4 + PZ, K157C + PZ, K157C + αMG, and K157C reacted with various MTS reagents + PZ or αMG. Following ANOVA, Tukey's honestly significant difference (HSD) post hoc test was applied to the entire data set shown in lines 1–14. MTSES, anionic sodium(2-sulfonatoethyl)methanethiosulfonate; MTSET, [(2-trimethylammonium)ethyl] methanethiosulfonate bromide. Statistical significance was accepted at an α-level of P < 0.05. *Significant statistical pairwise comparisons between lines 3 and 5 and between lines 4 and 6.