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Basal rates of glycolysis and LVP in untreated perfused working rat hearts and hearts treated with the PI3K inhibitor LY-294002 (10 μM) or the AC inhibitor NKY80 (20 μM)
| LVP, mmHg | Glycolytic Rate, μmol·g−1·min−1 | |
|---|---|---|
| Untreated | 109±7 | 3.19±0.40 |
| LY-294002 (10 μM) | 116±7 | 3.16±0.37 |
| NKY80 (20 μM) | 95±5 | 3.24±0.42 |
Values are means ± SE; n = 9–31/group. LVP, left ventricular pressure; PI3K, phosphoinositide 3-kinase; AC, adenylate cyclase. See materials and methods for calculations.
