Figure 3.

Anti-rabCD14 inhibits release of TNF (A) and IL-8 (B) into serum of rabbits receiving three sequential i.v. injections of LPS (5 μg/kg) at t = 0, 5, and 24 hr (filled symbols). As described in the Fig. 2 legend, animals that received LPS were either untreated (•), prophylactically treated with anti-rabCD14 (■, t = −1, 4, and 23 hr), or received anti-rabCD14 delayed treatment (▴, t = 4 and 23 hr). Control animals that did not receive LPS (○) were either untreated (no antibody) or received antibody prophylactic treatment or delayed treatment.