Table 1.
Baseline characteristics of hypertensive patients with type 2 diabetes and normal urinary albumin excretion in the study group as a whole and according to ACE inhibitor therapy (yes or no)
| Overall | ACE inhibitor yes | ACE inhibitor no | |
|---|---|---|---|
| n | 799 | 423 | 376 |
| Age (years) | 61.6 ± 8.0 | 61.5 ± 7.8 | 61.7 ± 8.2 |
| Male sex | 443 (55.4) | 238 (56.3) | 205 (54.5) |
| BMI (kg/m2) | 29.1 ± 4.8 | 29.2 ± 5.1 | 29.1 ± 4.6 |
| Known duration of diabetes (years) | 7.5 ± 6.5 | 7.5 ± 6.6 | 7.6 ± 6.3 |
| Smokers | |||
| Never | 435 (54.4) | 213 (50.4) | 222 (59.0)* |
| Former | 257 (32.2) | 147 (34.7) | 110 (29.3) |
| Current | 107 (13.4) | 63 (14.9) | 44 (11.7) |
| A1C (%)† | 5.8 ± 1.4 | 5.7 ± 1.4 | 5.7 ± 1.3 |
| Glucose (mg/dl) | 160.4 ± 45.7 | 159.1 ± 45.6 | 161.9 ± 45.9 |
| Trough blood pressure (mmHg) | |||
| Systolic | 150.4 ± 14.0 | 150.0 ± 14.0 | 150.9 ± 14.0 |
| Diastolic | 87.6 ± 7.5 | 87.5 ± 8.0 | 87.8 ± 7.0 |
| Mean arterial pressure | 108.6 ± 8.3 | 108.3 ± 8.5 | 108.9 ± 8.0 |
| Urinary albumin excretion (μg/min) | 5.2 (3.6–8.9) | 5.2 (3.6–9.3) | 5.2 (3.6–8.8) |
| Serum creatinine (μmol/l) | 79.6 ± 17.7 | 79.6 ± 17.7 | 79.6 ± 17.7 |
| Triglycerides (mmol/l) | 1.65 ± 0.91 | 1.63 ± 0.83 | 1.66 ± 1.00 |
| Cholesterol (mmol/l) | 5.41 ± 0.93 | 5.33 ± 0.93 | 5.50 ± 0.93* |
| Sokolow-Lyon voltage (mV) | 19.2 ± 5.8 | 19.2 ± 5.9 | 19.2 ± 5.7 |
| Cornell voltage (mV) | 13.4 ± 4.2 | 13.2 ± 4.2 | 13.6 ± 4.2 |
Data are means ± SD, n (%), or median (interquartile range).
*
P < 0.05 versus ACE inhibitor yes.
†
A1C was measured by ion-exchange high-performance liquid chromatography (normal range 3.5–5.2%).