Table 1.
Baseline characteristics of participants and age-adjusted univariate analyses of reproductive risk factors and the risk of dysglycemia
| Dysglycemia | No dysglycemia | P value (unadjusted) | Age-adjusted OR (95% CI) of dysglycemia | |
|---|---|---|---|---|
| n | 6,298 | 8,363 | ||
| Age (years) | 55.1 ± 11.1 | 50.0 ± 10.0 | <0.0001 | NA |
| Number of children | 2.74 ± 1.6 | 2.53 ± 1.3 | <0.0001 | 1.05 (1.04–1.06) |
| Low socioeconomic states | 2,243 (37.7) | 2,636 (33.2) | <0.0001 | 1.09 (1.01–1.17) |
| Non-European ancestry | 3,339 (53.0) | 4,649 (55.6) | 0.002 | 1.10 (1.02–1.17) |
| Preeclampsia/eclampsia | 700 (11.0) | 853 (10.1) | 0.10 | 1.19 (1.07–1.32) |
| Irregular periods | 608 (9.6) | 734 (8.8) | 0.08 | 1.22 (1.09–1.38) |
| GDM | 588 (9.4) | 673 (8.1) | 0.01 | 1.58 (1.40–1.78) |
| Early menopause | 124 (2.0) | 217 (2.6) | 0.01 | 1.24 (0.99–1.56) |
| BMI (kg/m2) | 31.6 ± 6.0 | 29.4 ± 6.0 | <0.0001 | 1.06 (1.06–1.07) |
Data are means ± SD and n (%) unless otherwise indicated. Dysglycemia indicates IFG, IGT, or type 2 diabetes, irregular periods indicates ≤6 menstrual cycles per year between the ages of 18 and 45 years not including pregnancy, and early menopause indicates permanent cessation of menses <45 years of age. NA, not applicable.